Biomarker innovations for critical conditions

Sometimes, in critically ill patients, the underlying pathomechanism behind the clinical symptoms is unclear. The research conducted at SphingoTec has identified key players involved in major pathways leading to mortality in critical care: bioactive Adrenomedullin (bio-ADM*) relevant for shock resulting from endothelial dysfunction, Proenkephalin A 119-159 (penKid*) preventing delayed recognition of loss of kidney function and Dipeptidyl Peptidase 3 (DPP3*) release resulting from dysregulated cell death. The innovative biomarkers allow for a better and faster understanding of the disease progression.