Disclaimer:
Sphingotest® penKid® and sphingotest® bio-ADM® are non-automated immunoluminometric assays for the in vitro diagnostic and are intended for the quantification of Proenkephalin A 119-159 and bioactive Adrenomedullin 1-52 (bio-ADM) in human EDTA plasma respectively. The assays are designed for the professional user in laboratory setting only.  

• The Proenkephalin A 119-159 measurement, in conjunction with clinical assessments and other laboratory findings, is used as an aid in the diagnosis of acute kidney injury (AKI) in adult patients with sepsis or septic shock. 
• Bioactive Adrenomedullin 1-52 measurement in conjunction with clinical assessments and other laboratory findings is used as an aid in the prediction of the need of vasopressor therapy in patients with sepsis or septic shock.

The measurement results need to be interpreted in conjunction with other clinical and laboratory data.
Sphingotest® penKid® and sphingotest® bio-ADM® are CE IVD-marked and hence certified and approved offered as CE IVD products for use in the European Economic Area (EEA) only. Human diagnostic use of such products may be subject to local regulations. The information contained in this communication does not constitute nor imply an offer to sell or transfer any product based on the SphingoTec microtiter plate (sphingotest®) as IVD product outside of EEA as in the United States of America or Canada.