Could it be Sepsis?

Deutschland erkennt Sepsis

In February 2021, the campaign #DeutschlandErkenntSepsis was initiated by Aktionsbündnis Patientensicherheit e.V., Sepsis-Stiftung, Deutsche Sepsis-Hilfe and Sepsis-Dialog of the University of Greifswald, and since July 2021, the campaign has been supported by the German Federal Ministry of Health. 

The campaign aims at raising awareness on the threats of sepsis among healthcare professionals and the public, to educate them about symptoms, diagnosis, treatment and prevention of sepsis. In order to deal with the numerous preventable deaths, “Could it be sepsis?” must become a normal question.

1 in 5  deaths worldwide are due to sepsis (1)

Could it be sepsis?

Sepsis is the body’s exaggerated response to an infection. It happens when an infection that already exists, triggers a chain reaction throughout your body. Infections that lead to sepsis most often start in the lungs or urinary tract. Sepsis is a global health challenge that is affecting over 49 million people every year, and at least 11 million people die of sepsis. That is one death every 2.8 seconds (2). 80% of sepsis cases occur outside hospitals, which emphasizes the need for awareness of sepsis and familiarization of its symptoms. 

 

Sepsis symptoms in adults and children (3):

  • Possible fever
  • Confusion or disorientation
  • Insomnia
  • Heart palpitations
  • Breathlessness
  • Accelerated breathing (≥ 22 breaths/minute)
  • Damp/cold or blotchy skin
  • Severe pain

Sepsis symptoms in neonates:

  • Feels abnormally cold and feverish
  • Breathing heavily
  • Repeated vomiting and/or diarrhea
  • Decreased food intake
  • Seizures
  • Slowed reactions
     

75%  of sepsis survivors suffer from its long-term effects for the rest of their lives impairing their day-to-day activities (4). 

Sepsis long-term consequences (5):

  • Severe reduction in the ability to cope with stress.
  • Reduced concentration.
  • Decreased responsiveness.
  • Attention problems.
  • Severely impaired memory.
  • Impaired vision and speech.
  • Balance problems and dizziness.
  • Breathing problems.
  • Muscle weakness.
  • Chronic pain, polyneuropathy.
  • Sleep disorders
     

In Germany, sepsis is the third most common cause of death after cardiovascular disease and cancer, with 75,000 documented deaths annually. The number of unreported cases is unknown as sepsis cases are often not recognized (5). At least 15,000 to 20,000 sepsis-related deaths per year are considered preventable in Germany through early detection, preventive measures (vaccinations and prophylaxis of hospital-acquired infections) and better treatment (5).

 

Every seven minutes, a person in Germany dies of sepsis (6).

Every half an hour, a person in Germany dies of sepsis, a mortality that could be prevented (6).

In SphingoTec, we commit to improving patient outcomes through our research and innovative biomarkers that support a personalized approach to individual patient. We do believe it is part of our responsibility to support #DeutschlandErkenntSepsis, and help to raise the awareness against this life-threatening emergency.

References:

(1)    University of Pittsburgh. "Sepsis associated with 1 in 5 deaths globally, double previous estimate." ScienceDaily. ScienceDaily, 16 January 2020. 
https://sciencedaily.com/releases/2020/01/200116121854.htm. Global Sepsis Alliance. https://www.global-sepsis-alliance.org

(2)    Sepsis Stiftung. Sepsis in pregnant women, premature babies, newborns, young children and adolescents. https://sepsis-stiftung.de/schwangerschaft-kinder-sepsis/

(3)    Scherag, A. et al. A patient cohort on long-term sequelae of sepsis survivors: study protocol of the Mid-German Sepsis Cohort. BMJ. (2017) DOI: dx.doi.org/10.1136/bmjopen-2017-016827

(4)    Fleischmann, C., Hartmann, M., Hartog, C. et al. Epidemiology of Sepsis in Germany: Incidence, Mortality And Associated Costs of Care 2007-2013. ICMx 3, A50 (2015). doi.org/10.1186/2197-425X-3-S1-A50

(5)    Deutschland Erkennt Sepsis. https://www.deutschland-erkennt-sepsis.de


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