Skip to main content
Logo SphingotecLogo Sphingotec
Request a Quote

Scientific Publications

SphingoTec's biomarker discovery is based on the highest standard of evidence, with over 100 publications, over 100 clinical studies, and more than 100.000 patients enrolled. Browse our scientific publications to learn more about how our biomarkers can impact patient care. You can use filters to narrow your search results by Year, Biomarker and Indications.

2020 penKid Sepsis

Incidence and outcome of sub-clinical acute kidney injury using penKid in critically ill patients

View the paper
2020 penKid Sepsis

Proenkephalin compared to conventional methods to assess kidney function in critically ill sepsis patients

View the paper
2020 penKid Other

Proenkephalin: a new biomarker for glomerular filtration rate and acute kidney injury

View the paper
2018 penKid Sepsis

Circulating proenkephalin, acute kidney injury, and its improvement in patients with severe sepsis or shock

View the paper
2017 penKid Heart Failure

Worsening renal function in heart failure: it takes 2 to tangle

View the paper
2017 penKid Other

Proenkephalin (PENK) as a Novel Biomarker for Kidney Function

View the paper
2020 penKid Major Surgery

Proenkephalin A 119-159 may predict post-operative acute kidney injury and in hospital mortality following open or endovascular thoraco-abdominal aortic repair

View the paper
2020 penKid Burns

PenKid measurement at admission is associated with outcome in severely ill burn patients

View the paper
2020 penKid Other

The effects of physical exercise on the assessment of kidney function

View the paper
2020 penKid Acute Kidney Injury

Recommendations on acute kidney injury biomarkers from the acute disease quality initiative consensus conference - a consensus statement

View the paper
2020 penKid Sepsis

Proenkephalin predicts organ failure, renal replacement therapy, and mortality in patients with sepsis

View the paper
2020 penKid Other

Proenkephalin as a new biomarker for pediatric acute kidney injury - reference values and performance in children under one year of age

View the paper
2020 bio-ADM penKid Sepsis

The value of plasma pro-enkephalin and adrenomedullin for the prediction of sepsis-associated acute kidney injury in critically ill patients

View the paper
2019 penKid Sepsis

Proenkephalin a 119–159 (penKid) – a novel biomarker for acute kidney injury in sepsis: an observational study

View the paper
2019 penKid Other

One-year prognosis of kidney injury at discharge from the ICU: A multicenter observational study

View the paper
2019 penKid Heart Failure

Proenkephalin and prognosis in heart failure with preserved ejection fraction: a GREAT network study

View the paper
2019 penKid Heart Failure

Proenkephalin, an opioid system surrogate, as a novel comprehensive renal marker in heart failure

View the paper
2018 penKid Heart Failure

Proenkephalin in heart failure

View the paper
2018 penKid Other

Proenkephalin and risk of developing chronic kidney disease: the prevention of renal and vascular end-stage disease study

View the paper
2018 penKid Sepsis

Proenkephalin A 119-159 (Penkid) is an early biomarker of septic acute kidney injury: the kidney in sepsis and septic shock (Kid-SSS) study

View the paper
2018 penKid Other

Back-to-back comparison of penKID with NephroCheck® to predict acute kidney injury at admission in intensive care unit: a brief report

View the paper
2018 penKid Other

Analytical performance of an immunoassay to measure proenkephalin

View the paper
2018 penKid Other

Proenkephalin for the early detection of acute kidney injury in hospitalized patients with chronic kidney disease

View the paper
2017 penKid Other

High Level of fasting plasma proenkephalin-A predicts deterioration of kidney function and incidence of CKD

View the paper
2017 penKid Heart Failure

Proenkephalin, renal dysfunction, and prognosis in patients with acute heart failure: A GREAT network study

View the paper
2017 penKid Major Surgery

Elevated soluble urokinase plasminogen activator receptor and proenkephalin serum levels predict the development of acute kidney injury after cardiac surgery

View the paper
2017 penKid Heart Failure

Clinical correlates and prognostic value of proenkephalin in acute and chronic heart failure

View the paper
2017 penKid Sepsis

Proenkephalin, neutrophil gelatinase-associated lipocalin, and estimated glomerular filtration rates in patients with sepsis

View the paper
2017 penKid Renal Transplantation

Plasma proenkephalin and poor long-term outcome in renal transplant recipients

View the paper
2016 penKid Heart Failure

Prognostic usefulness of proenkephalin in stable ambulatory patients with heart failure

View the paper
2015 penKid Cardiogenic Shock

Proenkephalin predicts acute kidney injury in cardiac surgery patients

View the paper
2014 penKid Acute myocardial infarction

Proenkephalin and prognosis after acute myocardial infarction

View the paper