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Innovative Acute Care Biomarkers

SphingoTec develops and markets innovative in vitro diagnostic (IVD) tests for novel and proprietary biomarkers for the diagnosis, prediction and monitoring of acute medical conditions, such as septic shock and circulatory failure, acute heart failure and acute kidney injury in order to support patient management and provide guidance for treatment strategies. The CE IVD tests for SphingoTec’s proprietary biomarkers are made available as sphingotest® microtiterplate tests as well as point-of-care tests on the Nexus IB10 immunoassay platform.

Three dimensional illustration of blood vessel with flowing erythrocytes and leukocytes.

bio-ADM

bio-ADM- endothelial function biomarker

Bioactive Adrenomedullin (bio-ADM) is a dynamic biomarker for the real time assessment of endothelial function. Loss of endothelial function is causing the formation of edema, shock and subsequent organ failure in critically ill patients.

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Human kidney cross section on blue, science background.

penKid

penKid - kidney function biomarker

Proenkephalin (penKid), is a dynamic biomarker for the real time assessment of kidney function. penKid is a blood-based alternative for detecting true GFR that is applicable in routine laboratory testing independent of inflammation and comorbidities.

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DPP3

DPP3 – cardiac depression factor

Dipeptidyl Peptidase 3 (DPP3), is a dynamic biomarker for assessing DPP3 release – one major cause of cardiac depression. The enzyme is at the core of a recently discovered disease mechanism leading to hemodynamic instability and short-term organ dysfunction.

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